cell cycle might influence the activity of AML cells by combination with PH-797804

No galactosidase exercise was apparent in HL 60 cells. Senescence is commonly connected with an improve in the cell cycle inhibitory proteins p15 or p16 which was not seen for THP one cells handled with PH-797804 . In contrast a marked improve in the senescence PH-797804 related PH-797804 TRAIL decoy receptor Dcr2 was observed, where as Dcr2 showed a marked decrease in HL 60 cells in which the PH-797804 induced apoptosis. in vitro The impact of PH-797804 on viable cell quantity,